Susac syndrome (SuS) is a rare immune-mediated occlusive microvascular endotheliopathy/basement membranopathy that causes ichemic injury to the retina, brain, and inner ear. SuS primarily affects young women 20-40 years of age . This disease is characterized by a clinical triad of encephalopathy, branch retinal artery occlusion (BRAO), and hearing loss, and is classically accompanied by "snowball" lesions in the corpus callosum on MRI. In this Webinar presentation we will discuss the clinical features, immunopathogenesis, diagnosis, clinical course, and treatment of SuS---with an emphasis on ophthalmologic aspects, particularly the important role of serial Ultra Wide-Field Fluorescein Angiography (UWF-FA) in the management of patients with SuS.
Lecturer: Dr. Robert Rennebohm, Cleveland, Ohio, USA